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Informational only

Listed as an EU cosmetic ingredient, not a medicine or a supplement for ingestion.

Cosmetic ingredient (EU)aka Matrixyl, Pal-KTTKS

Palmitoyl pentapeptide-4 — Profile & Reference (2026)

Last updated 2026-06-30

Palmitoyl pentapeptide-4 (also known as Matrixyl) is a peptide catalogued under Skin (Signal peptide (collagen synthesis)). It is described as: Collagen I/III/IV stimulation. Documented context: Anti-aging skincare. Neutral reference entry; EU status: EU cosmetic ingredient.

Mechanism / target

Collagen I/III/IV stimulation.

Documented context

Reported research or therapeutic context: Anti-aging skincare. This is neutral reference information, not a usage recommendation or medical advice.

Source: en.wikipedia.org ↗

Full sourced guide in progress

We publish a complete, primary-source-cited guide only once we can verify at least five PubMed/clinical references. This profile is intentionally a concise, sourced reference entry until then — we do not pad pages with unverified citations. The quick facts and source link above reflect what we can state reliably today.

This article is for educational and research purposes only. Peptides discussed here are not approved for human consumption by the FDA, EMA, or equivalent regulators outside of specific clinical contexts. Always consult a licensed medical professional before any therapeutic use.